Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse

Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse

Microglia, the resident immune cells of the brain parenchyma, are highly responsive to tissue injury. Following cell damage, microglial processes redirect their motility from randomly scouting the extracellular space to specifically reaching toward the compromised tissue. While the cell morphology a...

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Bibliographic Details
Main Authors: Amir ePozner, Ben eXu, Sierra ePalumbos, J. Michael Gee, Petr eTvrdik, Mario R. Capecchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Microglia
GECI
calcium imaging
purinergic receptors
GCaMP5G
PC::G5-tdT
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00012/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00012/full

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