Efficacy of Tie2 Receptor Antagonism in Angiosarcoma

Angiosarcomas are malignant endothelial cell tumors with few effective systemic treatments. Despite a unique endothelial origin, molecular candidates for targeted therapeutic intervention have been elusive. In this study, we explored the tunica internal endothelial cell kinase 2 (Tie2) receptor as a...

Full description

Bibliographic Details
Main Authors: Jason R. Hasenstein, Kelsey Kasmerchak, Darya Buehler, Gholam Reza Hafez, Kevin Cleary, John S. Moody, Kevin R. Kozak
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861280042X