Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model.

Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model.

<h4>Background</h4>The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. This study aims to directly determine the contribution of relapses to the burden of P. vivax...

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Bibliographic Details
Main Authors: Leanne J Robinson, Rahel Wampfler, Inoni Betuela, Stephan Karl, Michael T White, Connie S N Li Wai Suen, Natalie E Hofmann, Benson Kinboro, Andreea Waltmann, Jessica Brewster, Lina Lorry, Nandao Tarongka, Lornah Samol, Mariabeth Silkey, Quique Bassat, Peter M Siba, Louis Schofield, Ingrid Felger, Ivo Mueller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001891

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https://doi.org/10.1371/journal.pmed.1001891

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