Mitochondrial regulation of acute extrafollicular B‐cell responses to COVID‐19 severity

Mitochondrial regulation of acute extrafollicular B‐cell responses to COVID‐19 severity

Abstract Background Patients with COVID‐19 display a broad spectrum of manifestations from asymptomatic to life‐threatening disease with dysregulated immune responses. Mechanisms underlying the detrimental immune responses and disease severity remain elusive. Methods We investigated a total of 137 A...

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Bibliographic Details
Main Authors: Tianyu Cao, Li Liu, Kelvin Kai‐Wang To, Chun‐Yu Lim, Runhong Zhou, Yue Ming, Ka‐Yi Kwan, Sulan Yu, Chun‐Yin Chan, Biao Zhou, Haode Huang, Yufei Mo, Zhenglong Du, Ruomei Gong, Luk‐Tsz Yat, Ivan Fan‐Ngai Hung, Anthony Raymond Tam, Wing‐Kin To, Wai‐Shing Leung, Thomas Shiu‐Hong Chik, Owen Tak‐Yin Tsang, Xiang Lin, You‐qiang Song, Kwok‐Yung Yuen, Zhiwei Chen
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Clinical and Translational Medicine
Subjects:
B‐cell suppression
COVID‐19
mitochondrial dysfunction
SARS‐CoV‐2
Online Access:https://doi.org/10.1002/ctm2.1025

Internet

https://doi.org/10.1002/ctm2.1025

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