Assessing the meaningful change threshold of Quality of Life in Depression Scale using data from two phase 3 studies of esketamine nasal spray

Abstract Background Major depressive disorder (MDD) directly impacts patients’ lives including symptoms, functioning and health-related quality-of-life (HRQoL). Patient-reported outcomes can capture these impacts, however interpretation of clinical meaningfulness of these measurements are often not...

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Bibliographic Details
Main Authors: Heather Rozjabek, Nan Li, Holger Hartmann, Dong Jing Fu, Carla Canuso, Carol Jamieson
Format: Article
Language:English
Published: SpringerOpen 2022-07-01
Series:Journal of Patient-Reported Outcomes
Subjects:
Online Access:https://doi.org/10.1186/s41687-022-00453-y