Evaluating the clinical significance of FLT3 mutation status in Syrian newly diagnosed acute myeloid leukemia patients with normal karyotype

Evaluating the clinical significance of FLT3 mutation status in Syrian newly diagnosed acute myeloid leukemia patients with normal karyotype

The FMS-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD) is one of the most prevalent mutations, affecting between 20 and 30 percent of cases in patients with acute myeloid leukemia (AML). The Patients with a FLT3-ITD mutation have a poor prognosis. In the present study, we investigated...

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Bibliographic Details
Main Authors: Yahia Moualla, Faten Moassass, Bassel AL-Halabi, Walid Al-achkar, Michael Georgeos, Haissam Yazigi, Atieh Khamis
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Acute myeloid leukemia (AML)
Novel mutation
Prognosis
FLT3-ITD mutation
EFS
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022031462

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http://www.sciencedirect.com/science/article/pii/S2405844022031462

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