Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways

Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways

Abstract Background Mounting evidence has showed that Tumor-associated calcium signal transducer 2 (Trop2) is upregulated in various kinds of human cancers and plays important roles in tumorigenesis. However, the expression status and functional significance of Trop2 in thyroid cancer are largely un...

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Bibliographic Details
Main Authors: Hongyu Guan, Zejun Guo, Weiwei Liang, Hai Li, Guohong Wei, Lijuan Xu, Haipeng Xiao, Yanbing Li
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cancer
Subjects:
Trop2
Thyroid cancer
Invasion
MMP2
MAPK
Online Access:http://link.springer.com/article/10.1186/s12885-017-3475-2

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http://link.springer.com/article/10.1186/s12885-017-3475-2

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