Dual Chemotherapeutic Loading in Oxalate Transferrin-Conjugated Polymersomes Incorporated into Chitosan Hydrogels for Site-Specific Targeting of Melanoma Cells

Dual Chemotherapeutic Loading in Oxalate Transferrin-Conjugated Polymersomes Incorporated into Chitosan Hydrogels for Site-Specific Targeting of Melanoma Cells

In this work, we developed a smart drug delivery system composed of poly (ethylene glycol)-<i>block</i>-poly (ε-caprolactone) (PEG-PCL)-based polymersomes (Ps) loaded with doxorubicin (DOX) and vemurafenib (VEM). To enhance targeted delivery to malignant melanoma cells, these drug-loaded...

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Bibliographic Details
Main Authors: Mariana de C. Aranha, Luciana M. R. Alencar, Eliana B. Souto, Daniel T. Kamei, André M. Lopes
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Pharmaceuticals
Subjects:
polymersomes (Ps)
PEG-PCL copolymers
chitosan hydrogels
doxorubicin
vemurafenib
oxalate transferrin (Tf)
Online Access:https://www.mdpi.com/1424-8247/17/9/1177

Internet

https://www.mdpi.com/1424-8247/17/9/1177

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