Interaction Tolerance Detection Test for Understanding the Killing Efficacy of Directional Antibiotic Combinations
ABSTRACT Combination treatments are commonly prescribed for enhancing drug efficacy, as well as for preventing the evolution of resistance. The interaction between drugs is typically evaluated near the MIC, using growth rate as a measure of treatment efficacy. However, for infections in which the ki...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2022-02-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.00004-22 |