Development and design of CRISPR-based diagnostic for Acinetobacter baumannii by employing off-target gene editing of sgRNA
Acinetobacter baumannii is widely recognized as a human opportunistic pathogen in nosocomial infections. The proliferation of multidrug-resistant strains of A. baumannii has presented an array of difficulties for clinical anti-infective therapies and diagnostic procedures, owing to the existence of...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
|
Series: | Informatics in Medicine Unlocked |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914824000182 |