Pharmacokinetic improvement provided by microneedle patch in delivering bee venom, a case study in combating scopolamine-induced neurodegeneration in mouse model

Pharmacokinetic improvement provided by microneedle patch in delivering bee venom, a case study in combating scopolamine-induced neurodegeneration in mouse model

Much research has shown Bee venom to be an effective neuroprotective agent. However, the usual transdermal injection of bee venom poses many pharmacokinetic disadvantages. Here, we compared the administration of bee venom via subcutaneous injection (SC) and via Microneedle patch (MN). Both administr...

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Bibliographic Details
Main Authors: Cong Duc Nguyen, Jaehee Yoo, Eun Jin An, Chang Yub Sung, Do Hyeon Jeong, Soo-Yeon Park, Jae-Hong Kim, Gihyun Lee
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Drug Delivery
Subjects:
Neurodegeneration
bee venom
melittin
microneedle patch
pharmacokinetic
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2022.2116129

Internet

https://www.tandfonline.com/doi/10.1080/10717544.2022.2116129

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