AUTO-TUNE: selecting the distance threshold for inferring HIV transmission clusters

Molecular surveillance of viral pathogens and inference of transmission networks from genomic data play an increasingly important role in public health efforts, especially for HIV-1. For many methods, the genetic distance threshold used to connect sequences in the transmission network is a key param...

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Main Authors: Steven Weaver, Vanessa M. Dávila Conn, Daniel Ji, Hannah Verdonk, Santiago Ávila-Ríos, Andrew J. Leigh Brown, Joel O. Wertheim, Sergei L. Kosakovsky Pond
格式: 文件
语言:English
出版: Frontiers Media S.A. 2024-07-01
丛编:Frontiers in Bioinformatics
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在线阅读:https://www.frontiersin.org/articles/10.3389/fbinf.2024.1400003/full