Adipose Tissue-Derived Mesenchymal Stem Cells Alter Metabolites of Brain Cholesterol Homeostasis in An Alzheimer’s Model

Adipose Tissue-Derived Mesenchymal Stem Cells Alter Metabolites of Brain Cholesterol Homeostasis in An Alzheimer’s Model

Objective: Disruption of cholesterol homeostasis in Alzheimer’s disease (AD) plays a crucial role in diseasepathogenesis, making it a potential therapeutic target. Mesenchymal stem cells (MSCs) show promise in treatingcognitive impairment and provide a novel therapeutic approach. This study aims to...

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Bibliographic Details
Main Authors: Mehrnaz Karimi Darabi, Zahra Nazeri, Arash Rafeeinia, Seyedeh Pardis Pezeshki, Alireza Kheirollah, Yaghoob Farbood, Maryam Adelipour, Shirin Azizidoost, Maryam Cheraghzadeh
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2023-11-01
Series:Cell Journal
Subjects:
alzheimer’s disease
desmosterol
7-dehydrocholesterol
24-hydroxycholesterol
27-hydroxycholesterol
Online Access:https://www.celljournal.org/article_706776_55ce9cce22b245beedb91d836b1c1605.pdf

Internet

https://www.celljournal.org/article_706776_55ce9cce22b245beedb91d836b1c1605.pdf

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