Quercetin Stimulates Insulin Secretion and Reduces the Viability of Rat INS-1 Beta-Cells

Quercetin Stimulates Insulin Secretion and Reduces the Viability of Rat INS-1 Beta-Cells

Background/Aims: Previously we described insulinotropic effects of Leonurus sibiricus L. plant extracts used for diabetes mellitus treatment in Traditional Mongolian Medicine. The flavonoid quercetin and its glycoside rutin, which exert anti-diabetic properties in vivo by interfering with insulin si...

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Bibliographic Details
Main Authors: Michael Kittl, Marlena Beyreis, Munkhtuya Tumurkhuu, Johannes Fürst, Katharina Helm, Anna Pitschmann, Martin Gaisberger, Sabine Glasl, Markus Ritter, Martin Jakab
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Flavonoid
Quercetin
Rutin
Insulin
INS-1
Beta-cells
Apoptosis
Viability
Current
Calcium
Potassium
KATP
Kir 6.2
ATP-sensitive
Online Access:http://www.karger.com/Article/FullText/445623

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http://www.karger.com/Article/FullText/445623

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