Mechanistic Insight into Binding of Huperzine A with Human Serum Albumin: Computational and Spectroscopic Approaches

Mechanistic Insight into Binding of Huperzine A with Human Serum Albumin: Computational and Spectroscopic Approaches

Human serum albumin (HSA) is the most abundant protein in plasma synthesized by the liver and the main modulator of fluid distribution between body compartments. It has an amazing capacity to bind with multiple ligands, offering a store and transporter for various endogenous and exogenous compounds....

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Bibliographic Details
Main Authors: Anas Shamsi, Moyad Shahwan, Mohd Shahnawaz Khan, Fahad A. Alhumaydhi, Suliman A. Alsagaby, Waleed Al Abdulmonem, Bekhzod Abdullaev, Dharmendra Kumar Yadav
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
Huperzine A
molecular dynamics simulation
fluorescence spectroscopy
human serum albumin
neurodegenerative disorders
drug–protein interactions
Online Access:https://www.mdpi.com/1420-3049/27/3/797

Internet

https://www.mdpi.com/1420-3049/27/3/797

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