Quillaja brasiliensis nanoparticle adjuvant formulation improves the efficacy of an inactivated trivalent influenza vaccine in mice

Quillaja brasiliensis nanoparticle adjuvant formulation improves the efficacy of an inactivated trivalent influenza vaccine in mice

The threat of viral influenza infections has sparked research efforts to develop vaccines that can induce broadly protective immunity with safe adjuvants that trigger robust immune responses. Here, we demonstrate that subcutaneous or intranasal delivery of a seasonal trivalent influenza vaccine (TIV...

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Bibliographic Details
Main Authors: Fernando Silveira, Mariana Rivera-Patron, Nikita Deshpande, Soledad Sienra, Jackeline Checa, María Moreno, Jose A. Chabalgoity, Samuel P. Cibulski, Mariana Baz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Quillaja brasiliensis saponins
adjuvant
ISCOM-matrices
protection
influenza virus
intranasal route
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163858/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163858/full

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