The recruitment mechanisms and potential therapeutic targets of podocytes from parietal epithelial cells

Abstract Podocytes are differentiated postmitotic cells which cannot be replaced after podocyte injury. The mechanism of podocyte repopulation after injury has aroused wide concern. Parietal epithelial cells (PECs) are heterogeneous and only a specific subpopulation of PECs has the capacity to repla...

Full description

Bibliographic Details
Main Authors: Lihua Ni, Cheng Yuan, Xiaoyan Wu
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-021-03101-z