Conserved Double Translation Initiation Site for Δ160p53 Protein Hints at Isoform’s Key Role in Mammalian Physiology

<i>p53</i> is the most commonly mutated gene in human cancers. Two fundamental reasons for this are its long protein isoforms protect from cancer, while its shorter C-terminal isoforms can support cancer and metastasis. Previously, we have shown that the Δ160p53 protein isoform enhances...

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Bibliographic Details
Main Authors: Maria José López-Iniesta, Shrutee N. Parkar, Ana Catarina Ramalho, Rafaela Lacerda, Inês F. Costa, Jingyuan Zhao, Luísa Romão, Marco M. Candeias
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/24/15844