Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke

<p>Abstract</p> <p>The toll-like receptors (TLRs) are a key component of host defense in the respiratory epithelium. Cigarette smoking is associated with increased susceptibility to infection, while COPD is characterised by bacterial colonisation and infective exacerbations. We fou...

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Bibliographic Details
Main Authors: Dorscheid Delbert R, Greene Catherine M, MacRedmond Ruth E, McElvaney Noel G, O'Neill Shane J
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/8/1/84