HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation

Abstract Lysine succinylation is one of the major post-translational modifications occurring on histones and is believed to have significant roles in regulating chromatin structure and function. Currently, histone desuccinylation is widely believed to be catalyzed by members of the SIRT family deace...

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Bibliographic Details
Main Authors: Jialun Li, Lu Lu, Lingling Liu, Xuelian Ren, Jiwei Chen, Xingzhi Yin, Yanhui Xiao, Jiwen Li, Gang Wei, He Huang, Wei Wei, Jiemin Wong
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00573-9