Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling <it>in vitro</it>

<p>Abstract</p> <p>Background</p> <p>Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, known as statins, are commonly used as cholesterol-lowering drugs. During the past decade, evidence has emerged that statins also have neuroprotective effects. Research i...

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Bibliographic Details
Main Authors: Brand Yves, Setz Cristian, Levano Soledad, Listyo Alwin, Chavez Eduardo, Pak Kwang, Sung Michael, Radojevic Vesna, Ryan Allen F, Bodmer Daniel
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/114