Renal NKCC2 Is Dual Regulated by the Synergy of 20-HETE and High-Fat Diet in CYP4F2 Transgenic Mice
Introduction: 20-Hydroxyeicosatetraenoic acid (20-HETE) is the metabolite of cytochrome P450, which modulates blood pressure by inhibiting renal sodium transport. However, the molecular mechanisms underlying the role of 20-HETE in the development of obesity-related hypertension remain unclear, neces...
Main Authors: | Jingjing Wu, Guangrui Lai, Fangjie Chen, Bijun Zhang, Yanyan Zhao |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2021-07-01
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Series: | Kidney & Blood Pressure Research |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/517382 |
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