Structural variants involved in high-altitude adaptation detected using single-molecule long-read sequencing

Structural variants involved in high-altitude adaptation detected using single-molecule long-read sequencing

Abstract Structural variants (SVs), accounting for a larger fraction of the genome than SNPs/InDels, are an important pool of genetic variation, enabling environmental adaptations. Here, we perform long-read sequencing data of 320 Tibetan and Han samples and show that SVs are highly involved in high...

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Bibliographic Details
Main Authors: Jinlong Shi, Zhilong Jia, Jinxiu Sun, Xiaoreng Wang, Xiaojing Zhao, Chenghui Zhao, Fan Liang, Xinyu Song, Jiawei Guan, Xue Jia, Jing Yang, Qi Chen, Kang Yu, Qian Jia, Jing Wu, Depeng Wang, Yuhui Xiao, Xiaoman Xu, Yinzhe Liu, Shijing Wu, Qin Zhong, Jue Wu, Saijia Cui, Xiaochen Bo, Zhenzhou Wu, Minsung Park, Manolis Kellis, Kunlun He
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44034-z

Internet

https://doi.org/10.1038/s41467-023-44034-z

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