TGF-β Inhibitors for Therapeutic Management of Kidney Fibrosis
Kidney fibrosis is a common pathophysiological mechanism of chronic kidney disease (CKD) progression caused by several underlying kidney diseases. Among various contributors to kidney fibrosis, transforming growth factor-β1 (TGF-β1) is the major factor driving fibrosis. TGF-β1 exerts its profibrotic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/15/12/1485 |