Distribution of QPY and RAH haplotypes of granzyme B gene in distinct Brazilian populations Distribuição dos haplótipos QPY e RAH do gene da granzima B em grupos populacionais brasileiros

Distribution of QPY and RAH haplotypes of granzyme B gene in distinct Brazilian populations Distribuição dos haplótipos QPY e RAH do gene da granzima B em grupos populacionais brasileiros

INTRODUCTION: The cytolysis mediated by granules is one of the most important effector functions of cytotoxic T lymphocytes and natural killer cells. Recently, three single nucleotide polymorphisms (SNPs) were identified at exons 2, 3, and 5 of the granzyme B gene, resulting in a haplotype in which...

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Bibliographic Details
Main Authors: Fernanda Bernadelli Garcia, Simone Kashima, Evandra Strazza Rodrigues, Israel Tojal Silva, Tathiane Maistro Malta, Larissa Deadame de Figueiredo Nicolete, Dimas Tadeu Covas, Helio Moraes-Souza
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2012-08-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Granzima B
SNP
Haplótipo QPY
Haplótipo RAH
População brasileira
Distribuição populacional
Granzyme B
QPY haplotype
RAH haplotype
Brazilian population
Population distribution
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000400016

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000400016

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