Cardiolipin Alters <italic toggle="yes">Rhodobacter sphaeroides</italic> Cell Shape by Affecting Peptidoglycan Precursor Biosynthesis

ABSTRACT Cardiolipin (CL) is an anionic phospholipid that plays an important role in regulating protein biochemistry in bacteria and mitochondria. Deleting the CL synthase gene (Δcls) in Rhodobacter sphaeroides depletes CL and decreases cell length by 20%. Using a chemical biology approach, we found...

Full description

Bibliographic Details
Main Authors: Ti-Yu Lin, William S. Gross, George K. Auer, Douglas B. Weibel
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02401-18