Synthesis and Effects of 4,5-Diaryl-2-(2-alkylthio-5-imidazolyl) Imidazoles as Selective Cyclooxygenase Inhibitors
Objective(s)In recent years highly selective COX-2inhibitors were withdrawn from the market because of an increased risk of cardiovascular complications. In this study we were looking for potent compounds with moderate selectivity for cox-2. So, four analogues of 4, 5-diaryl-2-(2-alkylthio-5-imidazo...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2010-09-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | http://www.mums.ac.ir/shares/basic_medical/basicmedjou/89/fall/a10.pdf |