ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis

ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis

Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment. Herein, we analyze the effect of ARHGAP18 on the regulation of EC alignment and e...

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Bibliographic Details
Main Authors: Angelina J. Lay, Paul R. Coleman, Ann Formaz‐Preston, Ka Ka Ting, Ben Roediger, Wolfgang Weninger, Martin A. Schwartz, Mathew A. Vadas, Jennifer R. Gamble
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
animal model
ARHGAP18
endothelial cell
atherosclerosis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.010057

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.010057

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