PHACTR1, a coronary artery disease risk gene, mediates endothelial dysfunction

PHACTR1, a coronary artery disease risk gene, mediates endothelial dysfunction

Genome-wide association studies (GWAS) have recently identified phosphatase and actin regulator-1 (PHACTR1) as a critical risk gene associated with polyvascular diseases. However, it remains largely unclear how PHACTR1 is involved in endothelial dysfunction. Here, by mining published datasets of hum...

Full description

Bibliographic Details
Main Authors: Xiaoxuan Ma, Meiming Su, Qingze He, Zhidan Zhang, Fanshun Zhang, Zhenghong Liu, Lu Sun, Jianping Weng, Suowen Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
endothelial dysfunction
inflammation
PHACTR1
cardiovascular disease
RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.958677/full

Similar Items

Similar Items