Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens

Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens

Heme oxygenase-1 (HO-1) catalyzes the degradation of heme molecules releasing equimolar amounts of biliverdin, iron and carbon monoxide. Its expression is induced in response to stress signals such as reactive oxygen species and inflammatory mediators with antioxidant, anti-inflammatory and immunosu...

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Bibliographic Details
Main Authors: Diego L. Costa, Eduardo P. Amaral, Bruno B. Andrade, Alan Sher
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
heme oxygenase-1
inflammation
immune response
infectious disease
intracellular pathogens
host directed therapy
Online Access:https://www.mdpi.com/2076-3921/9/12/1205

Internet

https://www.mdpi.com/2076-3921/9/12/1205

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