Update on poly(ADP-ribose) polymerase inhibitors resistance in ovarian cancer

Update on poly(ADP-ribose) polymerase inhibitors resistance in ovarian cancer

Ovarian cancer is one of the most common reproductive system tumors. The incidence of ovarian cancer in China is on the rise. Poly(ADP-ribose) polymerase (PARP) inhibitor (PARPi) is a DNA repair enzyme associated with DNA damage repair. PARPi takes PARP as a target to kill tumor cells, especially fo...

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Bibliographic Details
Main Authors: Ruihong Dong, Ting Ding, Zhengyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
poly ADP-ribose polymerase inhibitors
ovarian cancer
drug resistance
mechanism
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1164395/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1164395/full

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