Genetic Polymorphisms of UDP-Glucuronosyltransferases and Susceptibility to Antituberculosis Drug-Induced Liver Injury: A Systematic Review and Meta-Analysis

Background and Aim. UDP-glucuronosyltransferases (UGTs) play an important role in drug metabolism and detoxification by catalyzing the glucuronidation reaction, which is associated with the occurrence of antituberculosis drug-induced liver injury (AT-DILI). The relationship between UGTs polymorphism...

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Bibliographic Details
Main Authors: Xinyu Chen, Zhuolu Hao, Nannan Wang, Jia Zhu, Honggang Yi, Shaowen Tang
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2023/5044451