HIF1α Genetic Variants and Protein Expressions Determine the Response to Platinum Based Chemotherapy and Clinical Outcome in Patients with Advanced NSCLC

HIF1α Genetic Variants and Protein Expressions Determine the Response to Platinum Based Chemotherapy and Clinical Outcome in Patients with Advanced NSCLC

Aim: To investigate whether the hypoxia-inducible factor-1α (HIF-1α) genetic variants and protein expression affect the chemotherapy response and the clinical outcome of patients with advanced non-small cell lung cancer (NSCLC). Methods: A total of 741 patients with histologically confirmed advanced...

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Bibliographic Details
Main Authors: Fenglei Wu, Jian Zhang, Yi Liu, Yigong Zheng, Nan Hu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Hypoxia-inducible factor-1α
Chemotherapy
Non-small cell lung cancer
Prognosis
Online Access:http://www.karger.com/Article/FullText/356593

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http://www.karger.com/Article/FullText/356593

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