The Role of Toll-Like Receptor-2 in Clostridioides difficile Infection: Evidence From a Mouse Model and Clinical Patients

The Role of Toll-Like Receptor-2 in Clostridioides difficile Infection: Evidence From a Mouse Model and Clinical Patients

BackgroundClostridioides difficile is the leading cause of nosocomial infectious diarrhea. Toll-like receptors (TLRs) are the major components of innate immunity that sense pathogens. The relationship between TLRs and C. difficile infection (CDI) was analyzed in clinical patients and a mouse model.M...

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Bibliographic Details
Main Authors: Yi-Hsin Lai, Bo-Yang Tsai, Chih-Yu Hsu, Yi-Hsuan Chen, Po-Han Chou, Yueh-Lin Chen, Hsiao-Chieh Liu, Wen-Chien Ko, Pei-Jane Tsai, Yuan-Pin Hung
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Clostridioides difficile infection
toll-like receptor
TLR2
rs3804099
tight junction
mice model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.691039/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.691039/full

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