m6A-mRNA Methylation Regulates Gene Expression and Programmable m6A Modification of Cellular RNAs With CRISPR-Cas13b in Renal Cell Carcinoma

m6A-mRNA Methylation Regulates Gene Expression and Programmable m6A Modification of Cellular RNAs With CRISPR-Cas13b in Renal Cell Carcinoma

Background: N6-methyladenosine (m6A) is the most extensive messenger RNA modification. Despite recent advances in the biological roles of m6A, its role in the development and progression of renal cell carcinoma (RCC) remains unclear.Methods: In this study, we gained the transcriptome-wide m6A profil...

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Bibliographic Details
Main Authors: Ying Gan, Aolin Li, Jun Liu, Xiaofei Wang, Zhenan Zhang, Qinhan Li, Xiongjun Ye, Lin Yao, Qian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Genetics
Subjects:
m6A
gene expression
Programmable Modification
CRISPR-Cas13b
Renal Cell Carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.795611/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.795611/full

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