Passive mechanical properties of the left ventricular myocardium and extracellular matrix in hearts with chronic volume overload from mitral regurgitation

Abstract Cardiac volume overload from mitral regurgitation (MR) is a trigger for left ventricular dilatation, remodeling, and ultimate failure. While the functional and structural adaptations to this overload are known, the adaptation of myocardial mechanical properties remains unknown. Using a rode...

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Bibliographic Details
Main Authors: Daniella Corporan, Maher Saadeh, Alessandra Yoldas, Jahnavi Mudigonda, Brooks Alexander Lane, Muralidhar Padala
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15305