Synthesis of 9-oxononanoyl cholesterol by ozonization1

A new route for the preparation of 9-oxononanoyl cholesterol (5) and its stable dimethylacetal (4) is described. The core aldehyde 5 is one of the major products formed during lipid peroxidation. The synthesis starts with the ozonization of oleic acid in methanol and further reduction with dimethyl...

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Bibliographic Details
Main Authors: Herbert Boechzelt, Barbara Karten, Peter M. Abuja, Wolfgang Sattler, Martin Mittelbach
Format: Article
Language:English
Published: Elsevier 1998-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520325323