YB1 modulates the DNA damage response in medulloblastoma

Abstract Y-box binding protein 1 (YBX1 or YB1) is a therapeutically relevant oncoprotein capable of RNA and DNA binding and mediating protein–protein interactions that drive proliferation, stemness, and resistance to platinum-based therapies. Given our previously published findings, the potential fo...

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Bibliographic Details
Main Authors: Leon F. McSwain, Claire E. Pillsbury, Ramona Haji-Seyed-Javadi, Sandip Kumar Rath, Victor Chen, Tiffany Huang, Shubin W. Shahab, Haritha Kunhiraman, James Ross, Gabrielle A. Price, Abhinav Dey, Dolores Hambardzumyan, Tobey MacDonald, David S. Yu, Christopher C. Porter, Anna M. Kenney
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35220-6