Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor

Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor

IntroductionImmune checkpoint blockade (ICB)-based therapy is revolutionizing cancer treatment by fostering successful immune surveillance and effector cell responses against various types of cancers. However, patients with HER2+ cancers are yet to benefit from this therapeutic strategy. Precisely,...

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Bibliographic Details
Main Authors: Regina Padmanabhan, Hadeel Kheraldine, Ishita Gupta, Nader Meskin, Anas Hamad, Semir Vranic, Ala-Eddin Al Moustafa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
HER2
PD-1/PD-L1
mathematical model
HER2/PD-1 interaction
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.977664/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.977664/full

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