Potential Blood DNA Methylation Biomarker Genes for Diagnosis of Liver Fibrosis in Patients With Biopsy-Proven Non-alcoholic Fatty Liver Disease

Potential Blood DNA Methylation Biomarker Genes for Diagnosis of Liver Fibrosis in Patients With Biopsy-Proven Non-alcoholic Fatty Liver Disease

Background and objectiveThis pilot study aimed to identify potential blood DNA methylation (BDM) biomarker genes for the diagnosis of liver fibrosis in non-alcoholic fatty liver disease (NAFLD).MethodsWe included a total of 16 NAFLD patients with significant (SLF, liver fibrosis stage ≥ 2) and 16 pa...

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Bibliographic Details
Main Authors: Qing-Feng Sun, Liang-Jie Tang, Ming-Jie Wang, Pei-Wu Zhu, Yang-Yang Li, Hong-Lei Ma, Ou-Yang Huang, Liang Hong, Gang Li, Christopher D. Byrne, Giovanni Targher, Wen-Yue Liu, Yan Lu, Ji-Guang Ding, Ming-Hua Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Medicine
Subjects:
NAFLD
liver fibrosis
blood DNA methylation
biomarker
MAFLD
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.864570/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.864570/full

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