Product-Related Impurities in Clinical-Grade Recombinant AAV Vectors: Characterization and Risk Assessment

Adeno-associated virus (AAV)-based vectors expressing therapeutic genes continue to demonstrate great promise for the treatment of a wide variety of diseases and together with other gene transfer vectors represent an emerging new therapeutic paradigm comparable in potential impact on human health to...

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Bibliographic Details
Main Author: J. Fraser Wright
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/2/1/80