Solulan C24- and Bile Salts-Modified Niosomes for New Ciprofloxacin Mannich Base for Combatting Pseudomonas-Infected Corneal Ulcer in Rabbits

Solulan C24- and Bile Salts-Modified Niosomes for New Ciprofloxacin Mannich Base for Combatting Pseudomonas-Infected Corneal Ulcer in Rabbits

Keratitis is a global health issue that claims the eye sight of millions of people every year. Dry eye, contact lens wearing and refractive surgeries are among the most common causes. The resistance rate among fluoroquinolone antibiotics is >30%. This study aims at formulating a newly synthesized...

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Bibliographic Details
Main Authors: Soad A. Mohamed, Mohamed A. Abdelgawad, Rania Alaaeldin, Zeinab Fathalla, Hossam Moharram, Raafat M. A. Abdallah, Islam M. Abdel-Rahman, Mohamed Abdel-Aziz, Gamal El-Din A. Abuo-Rahma, Mohammed M. Ghoneim, Alaa M. Hayallah, Mahmoud Elrehany, Hamdy Abdelkader
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceuticals
Subjects:
ciprofloxacin mannich base
keratitis
corneal ulcer
gene expression
antibiotic resistance
Online Access:https://www.mdpi.com/1424-8247/15/1/44

Internet

https://www.mdpi.com/1424-8247/15/1/44

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