Lipid droplet biogenesis and COX-2 pathway activation are triggered by Barrett’s esophagus and adenocarcinoma, but not esophageal squamous cell carcinoma risk factors

Abstract Esophageal cancer (EC) is an aggressive disease, presenting two main histological subtypes: adenocarcinoma (EAC) and squamous cell carcinoma (ESCC). The two EC subtypes widely differ concerning virtually all factors. ESCC development is mainly associated with tobacco and alcohol abuse, wher...

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Bibliographic Details
Main Authors: N. Carrossini, N. Meireles Da Costa, E. Andrade-Barreto, V. P. L. Sousa, P. Nicolau-Neto, P. T. Souza-Santos, G. R. Mansur, L. Wernersbach, P. T. Bozza, J. P. B. Viola, Luis Felipe Ribeiro Pinto
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80035-4