CRISPR/Cas9 mediated approach to generate YAP-depleted human embryonic stem cell line (MUSIe002-A-1)

Yes-associated protein (YAP), an important effector protein of the Hippo signaling pathway, acts as a molecular switch in controlling cell proliferation and apoptosis. In this study, a YAP-targeted isogenic sub-clone of the MUSIe002-A was generated, designated as MUSIe002-A-1. The MUSIe002-1 cell li...

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Bibliographic Details
Main Authors: Sujittra Khampang, Nittaya Jiamvoraphong, Chuti Laowtammathron, Chanchao Lorthongpanich, Phatchanat Klaihmon, Pimonwan Srisook, Xing Kang, Sudjit Luanpitpong, Yaowalak U-pratya, Surapol Issaragrisil
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122003397