Towards Atropoenantiopure N–C Axially Chiral Compounds via Stereoselective C–N Bond Formation

N–C axial chirality, although disregarded for decades, is an interesting type of chirality with appealing applications in medicinal chemistry and agrochemistry. However, atroposelective synthesis of optically pure compounds is extremely challenging and only a limited number of synthetic routes have...

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Bibliographic Details
Main Authors: Johanna Frey, Sabine Choppin, Francoise Colobert, Joanna Wencel-Delord
Format: Article
Language:deu
Published: Swiss Chemical Society 2020-11-01
Series:CHIMIA
Subjects:
Online Access:https://www.ingentaconnect.com/contentone/scs/chimia/2020/00000074/00000011/art00007