Molecular docking studies and molecular dynamic simulation analysis: To identify novel ATP-competitive inhibition of Glycogen synthase kinase-3β for Alzheimer’s disease [version 1; peer review: 2 approved, 1 not approved]

Molecular docking studies and molecular dynamic simulation analysis: To identify novel ATP-competitive inhibition of Glycogen synthase kinase-3β for Alzheimer’s disease [version 1; peer review: 2 approved, 1 not approved]

Background The discovery of an ideal and effective therapy is urgently required for the treatment of Alzheimer’s disease. The main pathological hallmarks of Alzheimer’s disease that appear before the clinical symptoms are neurofibrillary tangles, amyloid plaques, brain inflammation, and neuronal atr...

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Bibliographic Details
Main Authors: Suggala Ramya Shri, Yogendra Nayak, Sreedhara Ranganath Pai
Format: Article
Language:English
Published: F1000 Research Ltd 2024-07-01
Series:F1000Research
Subjects:
Alzheimer’s disease
GSK-3β
ATP-competitive study
Protein preparation
Ligand Preparation
Qikprop
eng
Online Access:https://f1000research.com/articles/13-773/v1

Internet

https://f1000research.com/articles/13-773/v1

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