K+‐independent Kir blockade by external Cs+ and Ba2+
Abstract Cations such as Cs+ and Ba2+ are known to block K+ currents by entering an open channel and binding to the selectivity filter, where they obstruct the pore and block diffusion of the permeant ion. This obstruction is voltage‐ and K+‐dependent and is relieved by the trans permeant ion flux....
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Format: | Article |
Language: | English |
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Wiley
2022-03-01
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Series: | Physiological Reports |
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Online Access: | https://doi.org/10.14814/phy2.15200 |