Mucociliary Wnt signaling promotes cilia biogenesis and beating
Motile cilia are thought of as signaling-inert nanomotors. Here, the authors show that motile cilia transduce a Wnt-protein phosphatase 1 signal that regulates cilia biogenesis and ciliary beating in Xenopus embryos and in human airway epithelia.
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-36743-2 |