Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer
Genetic mutation, chromosomal rearrangement and copy number amplification are common mechanisms responsible for generating gain-of-function, cancer-causing alterations. Here we report a new mechanism by which premature cleavage and polyadenylation (pPA) of RNA can produce an oncogenic protein. We id...
| Asıl Yazarlar: | , |
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| Materyal Türü: | Makale |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
eLife Sciences Publications Ltd
2016-05-01
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| Seri Bilgileri: | eLife |
| Konular: | |
| Online Erişim: | https://elifesciences.org/articles/14730 |