Structure of a bacterial RNA polymerase holoenzyme open promoter complex

Structure of a bacterial RNA polymerase holoenzyme open promoter complex

Initiation of transcription is a primary means for controlling gene expression. In bacteria, the RNA polymerase (RNAP) holoenzyme binds and unwinds promoter DNA, forming the transcription bubble of the open promoter complex (RPo). We have determined crystal structures, refined to 4.14 Å-resolution,...

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Bibliographic Details
Main Authors: Brian Bae, Andrey Feklistov, Agnieszka Lass-Napiorkowska, Robert Landick, Seth A Darst
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
open promoter compex
RNA polymerase
transcription
X-ray crystallography
Thermus aquaticus
Online Access:https://elifesciences.org/articles/08504

Internet

https://elifesciences.org/articles/08504

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